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How Is Streptococcus Pneumoniae Able To Avoid Destruction By A Phagocyte?

How Is Streptococcus Pneumoniae Able To Avoid Destruction By A Phagocyte?. To its complete encapsulation by host cell plasma membrane. Bacteria such as staphylococcus aureus and streptococcus pyogenes produce the exotoxin leukocidin which damages the cytoplasmic membrane of the phagocyte.

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In the absence of antibody, it resists phagocytosis and replicates extracellularly in mammalian tissues. Pneumoniae causes otitis media in children and sepsis in patients infected with the human immunodeficiency virus ().one of the virulence factors. Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide.

The Phagocyte Cannot Engulf The Encapsulated Cells, Allowing The Bacterium To Become Established And Cause Disease In The Host.


Streptococcus pneumoniae is a major pathogen in humans. The principal defense against infection is ingestion by dendritic and phagocytic cells; Within a period of one to a few minutes.

Pneumonia Is Currently The Most Common.


Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide. Many bacterial cells secrete some extracellular material in the form of a capsule or a slime layer. Pneumoniae needs to evade host immunity and replicate in the host after colonization.

Pneumoniae) And By Inhibiting Bacterial Interactions With Nonopsonic Phagocytic Receptors Such As Mannose Or Scavenger Receptors (2, 3).


Some bacteria develop defenses of their own to avoid phagocytosis. Pneumoniae.currently, 98 immunologically and structurally distinct cps types. Streptococcus pneumoniae occupies an important position in the history of microbiology:

Pneumococci Are Common Inhabitants Of The Respiratory Tract.


Capsules can be seen under a light microscope by placing the. Bacteria such as staphylococcus aureus and streptococcus pyogenes produce the exotoxin leukocidin which damages the cytoplasmic membrane of the phagocyte. Exotoxin protein a produced by staphylococcus aureus blocks opsonization with igg.

The Pathogenicity Of This Organism Is Related To Its Many Virulence Factors, The Most Important Of Which Is The Thick Pneumococcal Capsule That Minimizes Phagocytosis.


In the absence of antibody, it resists phagocytosis and replicates extracellularly in mammalian tissues. Streptococcus pneumoniae has a high genetic diversity, and certain lineages are particularly successful. During the process of invasive infection, s.

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